Dr. Laurence TIRET
Director of Research at the French Institute for Medical Research, Inserm, Paris, France

Laurence Tiret received her PhD in Mathematical Statistics from Paris VI University in 1978. After having worked for 15 years in the field of epidemiology and public health, she shifted her interest to genetic epidemiology, and more particularly to genetics of cardiovascular diseases. Her main research interests concern the development of novel strategies and methods for analysis of the genetic component of complex diseases and their application to large epidemiological studies aimed at identifying susceptibility genes to common cardiovascular disorders. In collaboration with Fran├žois Cambien, she has done pioneering work in the characterization of the sequence variability and the structure of linkage disequilibrium in human genes. She also pioneered research in the field of system genetics as exemplified by various studies of inflammatory gene systems in atherothrombosis. Her research interest is now moving to genome-wide approaches aimed at discovering new pathophysiological mechanisms of disease using high-throughput DNA chips. Laurence Tiret has authored or co-authored over 150 publications and is regularly invited to give lectures in the field of genetics of cardiovascular diseases. She has served as a member of the Cardiovascular Scientific Commission of INSERM and is member of several steering committees of large European projects.